It's very convenient running direct in, whether late night recording, practicing at home, or gigging at church or a club. In this video I'll compare running direct in with pedals into an amp (using a Two Notes Captor) versus running direct in with pedals only.
PLEASE NOTE: You never want to run direct into your DAW or soundboard from the speaker output unless your amp has an output made for this reason.
Jam tracks used http://www.youtube.com/channel/UC55xyo8HvJMuTROnqpPgG5Q