Here is how I would setup the Zoom G3 as a part of my pedalboard in front of an amp. I'm really impressed so far.
First is a compressor, then fuzz, then Distortion + for overdrive, then .8th digital delay, then 1/4 modulated delay, then I have a reverb set always on last in the chain.
Guitar is a Warmoth Telecaster with a Goncalo Alves/pau Ferro neck and Fralin SP43/Vintage Hot pickups. Amp is a Dr. Z Maz 38 Sr.